Supplemental Table.

1: Individual Components of the Composite Outcome for Severe COVID-19 Infection by Level of Cardiac Troponin Elevation

	Normal cTn,≤ 1x ULN	Mild cTn Elevation,> 1 to < 2x ULN	Severe cTn Elevation,≥ 2x ULN	P -value
n	658	69	46
60-Day Mortality (%)	91 (13.8)	20 (29.0)	24 (52.2)	<0.001
Need for ICU (%)	268 (40.7)	47 (68.1)	41 (89.1)	<0.001
NIPPV (%)	40 (6.1)	1 (1.4)	6 (13.0)	0.039
Mechanical Ventilation (%)	170 (25.8)	33 (47.8)	33 (71.7)	<0.001
Overall Composite (%)	288 (43.8)	49 (71.0)	43 (93.5)	<0.001

cTn = cardiac troponin; ULN = upper limit of normal; ICU = intensive care unit; NIPPV = non-invasive positive pressure ventilation