Skip to main content
. Author manuscript; available in PMC: 2022 Jan 22.
Published in final edited form as: ACS Appl Nano Mater. 2020 Dec 23;4(1):33–42. doi: 10.1021/acsanm.0c01998

Figure 1.

Figure 1.

Schematic of the fabrication of SWNT-derivatized substrates. The method contains four main steps for the newly developed avidin platforms (a,b) and three steps for the APTES platforms (c,d), which serve as the current standard method of SWNT sensor attachment to a glass surface. The first step, outlined in red, is the addition of the piranha solution to the glass slides to generate hydroxyl groups at the surface. Next, epoxy silane, outlined in light green, or aminopropyl silane, outlined in dark green, is added and reacts with the exposed hydroxyl groups and bind to the surface. For avidin platforms, there is one more step than for the APTES platforms, outlined in blue is the addition of the avidin group. The final step for both platforms is the addition of the SWNT. The biotinylated SWNT will interact with the avidin on the platform to create a strong noncovalent bond. The nonbiotinylated SWNT interacts with the avidin platform through electrostatic interactions. Both the biotinylated and non-biotinylated SWNT interact with the APTES surface through electrostatic interactions.