Table 4.
Information on 27 genes previously reported to be associated with hyperthermia
| Gene | Title of related article | PMID |
|---|---|---|
| NFKBIA | Short-term hyperthermia prevents activation of proinflammatory genes in fibroblast-like synoviocytes by blocking the activation of the transcription factor NF-kappaB. | 16955275 |
| CCL20 | Local hyperthermia decreases the expression of CCL-20 in condyloma acuminatum. | 21050487 |
| TNF | Comparative in vitro studies of the potentiation of tumor necrosis factor (TNF)-alpha, TNF-beta, and TNF-SAM2 cytotoxicity by hyperthermia. | 1571335 |
| GRPR | How gastrin-releasing peptide receptor (GRPR) and α(v)β(3) integrin expression reflect reorganization features of tumors after hyperthermia treatments. | 28761146 |
| CD44 | CD44-targeted magnetic nanoparticles kill head and neck squamous cell carcinoma stem cells in an alternating magnetic field. | 31571863 |
| GDF15 | Involvement of ERK1/2 signalling and growth-related molecules’ expression in response to heat stress-induced damage in rat jejunum and IEC-6 cells. | 20707649 |
| CX3CL1 | Heat therapy promotes the expression of angiogenic regulators in human skeletal muscle. | 27357800 |
| ID1 | Correlation between the expression of Id-1 and hyperthermia-associated molecules in oral squamous cell carcinoma. | 23723304 |
| GCK | Cellular signalling after in vivo heat shock in the liver. | 10772775 |
| CEBPE | Gene networks involved in apoptosis induced by hyperthermia in human lymphoma U937 cells. | 19732844 |
| HSPA8P11 | The cellular and molecular basis of hyperthermia. | 12098606 |
| TRPV4 | Ischemic brain injury leads to brain edema via hyperthermia-induced TRPV4 activation. | 29793978 |
| ADORA1 | Activation of central adenosine A(2A) receptors lowers the seizure threshold of hyperthermia-induced seizure in childhood rats. | 21144776 |
| CTGF | Role of CTGF in sensitivity to hyperthermia in ovarian and uterine cancers. | 27806300 |
| COL1A1 | Molecular pathology of vertebral deformities in hyperthermic Atlantic salmon (Salmo salar). | 20604915 |
| MEDAG | Hyperthermia severely affects the vascular effects of MDMA and metabolites in the human internal mammary artery in vitro. | 28084566 |
| GPC3 | Glypican-3 (GPC3) targeted Fe3O4 core/Au shell nanocomplex for fluorescence/MRI/photoacoustic imaging-guided tumor photothermal therapy. | 31603456 |
| FN1 | Role of CTGF in sensitivity to hyperthermia in ovarian and uterine cancers. | 27806300 |
| TLR2 | Extracellular heat shock protein 70 mediates heat stress-induced epidermal growth factor receptor transactivation in A431 carcinoma cells. | 17126326 |
| VCAN | Versican and vascular endothelial growth factor expression levels in peritoneal metastases from colorectal cancer are associated with survival after cytoreductive surgery and hyperthermic intraperitoneal chemotherapy. | 26873137 |
| MMP2 | Hyperthermia inhibits the motility of gemcitabine-resistant pancreatic cancer PANC-1 cells through the inhibition of epithelial-mesenchymal transition. | 29568909 |
| NQO1 | Anti-cancer effect of bio-reductive drug beta-lapachon is enhanced by activating NQO1 with heat shock. | 18283592 |
| H2AFY2 | Proteomic and bioinformatic analysis of condyloma acuminata: mild hyperthermia treatment reveals compromised HPV infectivity of keratinocytes via regulation of metabolism, differentiation and anti-viral responses. | 30909744 |
| JAM3 | Core temperature correlates with expression of selected stress and immunomodulatory genes in febrile patients with sepsis and noninfectious SIRS. | 19496026 |
| TGIF2 | Involvement of ERK1/2 signalling and growth-related molecules’ expression in response to heat stress-induced damage in rat jejunum and IEC-6 cells. | 20707649 |
| EGF | Effect of hyperthermia on invasion ability and TGF-β1 expression of breast carcinoma MCF-7 cells. | 21455587 |
| NFE2 | Hyperthermia and protein homeostasis: cytoprotection and cell death. | 32716865 |