Table 1.
Group | Animal number | Preoperative tumor volumetry (mm3) | Postoperative tumor volumetry (mm3) | Radicality of tumor resection (%) |
---|---|---|---|---|
Cyclophosphamide + DNAmix | 1_1 | 4.692 | 0 | 100* |
1_2 | 3.103 | 0 | 100* | |
1_3 | 5.622 | 2.222 | 61† | |
1_4 | 2.446 | 0 | 100* | |
Cyclophosphamide | 2_1 | 5.662 | 0 | 100* |
2_2 | 2.818 | 2.718 | – | |
2_3 | 1.974 | 0 | 100* | |
2_4 | 63.364 | 16.251 | 75† | |
Control | 3_1 | 3.434 | 0 | 100* |
3_2 | 41.736 | 16.548 | 61† | |
3_3 | 0.134 | 0.239 | – | |
3_5 | 5.106 | 0 | 100* |
*Total resection. †Partial resection. BBB, blood–brain barrier; CNS, central nervous system; CP, cyclophosphamide; CSC, cancer stem cell; DC, dendritic cell; dsDNA, double-stranded DNA; HR, homologous repair; ICL, interstrand cross-link; MDSC, myeloid-derived suppressor cell; MMC, mitomycin C; MOF, multiple organ failure; MTIC, monomethyl triazen imidazole carboxamide; NER, nucleotide excision repair; TM, tail moment; TMZ, temozolomide.