Table 1.

Pharmacokinetics parameters for scutellarin, Scu-Me-C5-TG and Scu-Me-C5-βMe-TG after oral administration in female rats (data are represented as mean ± SD, n = 5).

Parameters	Units	Scu	Scu-Me-C5-TGa	Scu-Me-C5-βMe-TGb,c
AUC(0–24 h)	μg/L*h	2098.6 ± 245.4	4697.6 ± 311.7	5146.4 ± 505.7
t max	h	0.32 ± 0.02	2.80 ± 1.09	2.40 ± 0.89
C max	μg/L	256.3 ± 18.0	441.8 ± 101.9	540.8 ± 108.9
t 1/2	h	8.6 ± 0.9	10.6 ± 1.9	6.5 ± 0.9
F rel	%	100.0	223.8	245.2

^aThe p-value between Scu and Scu-Me-C5-TG is <.001.

^bThe p-value between Scu and Scu-Me-C5-βMe-TG is <.001.

^cThe p-value between Scu-Me-C5-TG and Scu-Me-C5-βMe-TG is <.05.