Table 2.

Stability study of optimized TC-SF-NPs at different temperatures and the humidity condition.

Stability condition	Time (month)	Particle size (nm)	Zeta potential (mV)	Initial amount of drug (mg)	Drug amount at the end of 3 months (mg)	% Degraded at the end of 3 months
25 ± 2 °C/60 ± 5% RH	0	186.12 ± 5.87	−19.21 ± 0.8	7.51 ± 0.12	7.42 ± 0.19	1.20
	1	187.31 ± 5.64	−19.42 ± 0.7
	3	189.24 ± 4.80	−20.02 ± 1.1
40 ± 2 °C/ 75 ± 5% RH	0	186.12 ± 5.87	−19.21 ± 0.6	7.51 ± 0.12	7.36 ± 0.13	1.99
	1	187.53 ± 6.25	−19.42 ± 0.9
	3	191.14 ± 4.86	−20.36 ± 1.3
5 ± 2 °C/ambient RH	0	186.12 ± 5.87	−19.21 ± 1.2	7.51 ± 0.12	7.46 ± 0.16	0.66
	1	187.63 ± 5.46	−19.42 ± 0.8
	3	187.54 ± 4.39	−20.16 ± 1.0

Data are given in mean ± SD (n = 3).