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Acute ulcerogenicity activity.
| Compounds | Number of rats with ulcer | Lesion Incidence (%) | Average Ulcer number | Ulcer Index (UI)a |
|---|---|---|---|---|
| Control | 0 | 0 | 0 | Nil |
| 4a | 3 | 60 | 1.6 | 8.26 |
| 4b | 1 | 20 | 0.8 | 3 |
| 7c | 3 | 60 | 1 | 8 |
| 13b | 2 | 40 | 0.4 | 4.8 |
| 14c | 2 | 40 | 0.8 | 5.3 |
| Indomethacin | 5 | 100 | 12.4 | 23.8 |
| Ibuprofen | 5 | 100 | 3.8 | 15 |
| Celecoxib | 1 | 20 | 0.2 | 2.4 |
aThe ulcer index (UI) was calculated according to the equation: (UI = UN + US + UPX10−1), (n = 5).
