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. 2021 Jul 29;80(1):1946324. doi: 10.1080/22423982.2021.1946324
PAEDIATRIC-RELATED DISEASES (n = 5)
Author (year, journal) Setting Topic Populations’ characteristics Outcomes Main results STROBE
He (2017, CMAJ) (87)

  • Quebec

  • Retrospective

 Hospitalisation

  • First Nations people (Gr 1)

  • Inuit people (Gr 2)

  • Non-Indigenous people (Gr 3)

  • <1 y.o.

  • F/M

 Adjusted rate ratios for infant hospitalisation (95% CI) Any cause:
Gr 1: 1.43 (1.37-1.50); Gr 2: 1.37 (1.24-1.52)
Infections:
Gr 1: 1.66 (1.54-1.78); Gr 2: 1.31 (1.10-1.57)
Injuries/accidents:
Gr 1: 1.16 (0.97-1.39); Gr 2: 1.36 (0.86-2.15)
Congenital anomalies:
Gr 1: 1.35 (1.15-1.59); Gr 2: 1.40 (1.01-1.95)
Perinatal-originated conditions:
Gr 1: 0.95 (0.75-1.19); Gr 2: 0.92 (0.58-1.45)
Respiratory system: First Nations: 1.91 (1.80-2.03)
Inuit: 1.82 (1.59-2.08)
Digestive system:
Gr 1: 1.49 (1.31-1.69); Gr 2: 1.01 (0.73-1.39)
Nervous system:
Gr 1: 1.64 (1.43-1.89); Gr 2: 1.64 (1.20-2.25)
Genitourinary system:
Gr 1: 1.75 (1.45-2.11); Gr 2: 0.61 (0.32-1.16)
Musculoskeletal system: Gr 1: 1.34 (0.60-2.98)
Circulatory system: Gr 1: 1.50 (0.86-2.61)
Endocrine system:
Gr 1: 1.49 (1.29-1.73); Gr 2: 2.61 (1.50-4.53)
Skin and subcutaneous tissue:
Gr 1: 3.00 (2.58-3.49); Gr 2: 2.86 (1.57-5.23)
Blood: Gr 1: 0.96 (0.57-1.60)
Mental/neurodevelopmental disorders:
Gr 1: 1.20 (0.50-2.95)
Neoplasms: Gr 1: 0.91 (0.50-1.71)		 18/22
Reime (2007, Paediatr Perinat Epidemiol) (24)

  • All of Canada

  • Retrospective

 ICU admissions

  • Indigenous people (Gr 1)

  • White people (Gr 2)

  • Neonates

  • F/M

 No access to prenatal care
Mortality (p <0.001)
Adjusted odds ratio for Gr 1 for specific treatments (95% CI)
Length of stay (days) (p<0.05)		 Gr 1: 7.2%; Gr 2: 1.6%
Gr 1: 7.1%; Gr 2: 7.4%
Transparenteral nutrition: 0.77 (0.60-1.00)
Blood transfusion 1.07 (0.78-1.46)
Surfactant 0.78 (0.57-1.06)
Assisted ventilation 0.86 (0.67-1.09)
Surgery 0.73 (0.54-0.99)
Antenatal steroids 1.04 (0.81-1.34)
Incubator 0.85 (0.65-1.12)
Gr 1: 4.5 days; Gr 2: 2.9 days		 19/22
Stammers (2014, Pediatr Blood Cancer) (81)

  • Manitoba

  • Retrospective

 Cancer complications
Hospitalisation

  • First Nations people (Gr 1)

  • Non-First Nations people (Gr 2)

  • <15 y.o.

  • F/M

 Risk ratios for hospital admission days for treatment complications for Gr 1 (95% CI; p) Low risk: 0.853 (0.27-1.55; p= 0.371)
Intermediate/High risk: 1.140 (0.52-2.48; p=0.748)		 18/22
Thanh (2015, J Pediatr) (125)

  • Alberta

  • Retrospective

 Health care utilisation for low birth-weight population

  • Indigenous people (Gr 1)

  • Alberta’s population (Gr 2)

  • <1 y.o.

  • F/M

 Health services use cost coefficient Gr 1: 1560 (1359-1762; p <0.001) 18/22
Thomson (1994, Can Fam Physician) (86)

  • Saskatchewan, Ontario

  • Retrospective

 Acute otitis media
Hospitalisation

  • First Nations people (Gr 1)

  • Ontario and Saskatchewan’s general population (Gr 2)

  • <5 y.o.

  • F/M

 Hospitalisation rates/100 for otitis media
(Gr 1/Gr 2)
Relative risk of hospitalisations for otitis media for Gr 1 (95% CI)
Hospitalisation rates/100 for upper respiratory tract infection (Gr 1/Gr 2)
Relative risk of hospitalisation for upper respiratory infection for Gr 1 (95% CI)		 Boys 1-4 y.o.: 6.7/1.1; Girls 1-4 y.o.: 5.6/0.8
0-1 y.o.: 2.1/0.3
Boys 1-4 y.o.: 6.1 (5.1-7.3); Girls 1-4 y.o.: 6.7 (5.4-8.2)
0-1 y.o.: 6.1 (0.6-67.0)
Boys 1-4 y.o.: 24.7/5.2; Girls 1-4 y.o.: 22.9/3.8
Saskatchewan’s boys 0-1 y.o.: 27.1/4.8
Saskatchewan’s girls 0-1 y.o.: 27.4/3.1
Ontario’s 0-1 y.o.: 5.2/0.7
Boys 1-4 y.o.: 4.7 (4.3-5.1); Girls 1-4 y.o.: 6.1 (5.6-6.7)
Saskatchewan’s boys 0-1 y.o.: 5.7 (4.8-6.7)
Saskatchewan’s girls 0-1 y.o.: 8.9 (7.4-10.6)
Ontario’s 0-1 y.o.: 7.7 (1.5-38.9)		 12/22