Table 7.
Immunoreactivity score (IRS) for immunochemical labelling of HPA peptides in NMCs found in CM/SM and control skin specimens
| Bioptate type (group) | Average NMCs number | Percentage of antigen-positive NMCs | Mean (group)1 | SD (group)1 | ||||
|---|---|---|---|---|---|---|---|---|
| CRH | UCN1 | CRHR1 | ACTH | MC1R | ||||
| CM/SM patients | 215 | 0.8 ±0.2 | 5.2 ±3.2 | 0.9 ±0.4 | 14.1 ±4.3* | 6.2 ±3.4 | 5.4 ±1.4** | 11 |
| Control skin | 58 | 0.3 ±0.2 | 1.0 ±0.4 | 0.5 ±0.2 | 4.2 ±1.6 | 1.4 ±0.5 | 1.5 ±0.4 | 2.4 |
1
ased on all IRS results obtainedfor a given group (group members * antigens).
*
p < 0.05
**
p < 0.005, CM/SM vs. control.