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MiR-223-3p overexpression reversed the inhibitory effects of Que on the MF and the expressions of Fibronectin and Col1A1 in ISO-reduced AF model rats. (a-b). HE and Masson staining were conducted to observe the changes in cardiac hypertrophy and fibrosis of ISO-reduced AF model rat. (c). The expressions of Col1A1 and Fibronectin were detected by immunohistochemical. All experiments were conducted three times. (Que: quercetin, ISO: isoprenaline, AF: atrial fibrillation)
