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. 2021 Jul 30;13(1):1941711. doi: 10.1080/19490976.2021.1941711

Table 2.

Advantages and limitations: administration of antibiotics

  Advantages Limitations
Drinking water (Table 4)
  • Suitable for repeated administration

  • Least stressful method

  • Good absorption in GI tract

  • Single housing necessary if the dose needs to be monitored

  • Consumption variability if grouped together

  • Unpalatability can restrict intake leading to dehydration26

Oral gavage
(Table 5)
  • Dosage monitored

  • Good absorption in GI tract

  • Not very suitable for repeated administration

  • The gavage procedure is stressful for the animal

  • Repeat dosing should be carried out at approx. the same time each day

  • Severe adverse effect if gavage tubes are incorrectly placed

  • Technically difficult method

Combination (Table 6)
  • Abx can be administered accordingly to their pharmacokinetics

  • Good absorption in GI tract