Table 3.

Clinical Predictors of Overall Survival

Characteristic	Univariate Cox		Multivariate Cox
	HR (95% CI)	P-value	HR (95% CI)	P-value
Age	1.01 (0.97–10.44)	.61
Sex	0.88 (0.56–1.36)	.56
Medical comorbidities
HTN	1.01 (0.66–1.55)	.96
T2DM	2.02 (1.22–3.34)	.01	1.44 (0.81–2.56)	.21
Dyslipidemia	0.81 (0.52–1.27)	.36
Smoking	1.28 (0.71–2.28)	.42
Afib	1.04 (0.48–2.26)	.92
CVD	1.39 (0.82–2.34)	.24
COPD	1.0 (0.40–2.49)	.99
Other CNS disease	1.39 (0.79–2.44)	.27
Previous history of cancer	1.48 (0.88–2.49)	.16
Number of comorbidities	1.14 (0.98–1.32)	.09
Multiple comorbidities	0.98 (0.64–1.50)	.94
Any comorbidity	1.05 (0.59–1.87)	.87
Hospital stay and treatment
Preop KPS	0.99 (0.97–1.0)	.14
Postop complication	2.83 (1.77–4.53)	<.0001	2.34 (1.19–4.6)	.01
Length of stay	0.46 (0.29–0.72)	.001	0.98 (0.97–0.99)	.03
Discharge home	0.50 (0.31–0.80)	.01	0.54 (0.27–1.05)	.07
EOR		.003
Biopsy	Reference
STR	0.33 (0.13–0.81)	.02	0.38 (0.15–0.98)	.046
GTR	0.17 (0.06–0.48)	.0007	0.24 (0.08–0.72)	.01
Adjuvant treatment		<.0001
None	Reference
Radiation only	0.27 (0.13–0.56)	.0005	0.37 (0.16–0.84)	.02
TMZ only	0.16 (0.04–0.57)	.005	0.08 (0.02–0.33)	.0005
Radiation + TMZ	0.09 (0.04–0.19)	<.0001	0.14 (0.06–0.33)	<.0001

Significant values (P-value < 0.05) are given in bold.