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. 2021 May 29;182(2):297–309. doi: 10.1093/toxsci/kfab065

Table 3.

Fold Changes for Genes in Alox15 Signaling Pathway

ID Fold Change Cells Expressing Gene in Cluster (%) Cells Expressing Gene in All Clusters (%)
Alox15 2.24905554 0.968 0.013
Fn1 3.11389901 1 0.314
Itgam 1.79166236 0.981 0.025
C3 0.54306139 0.614 0.148

After scRNAseq, a unique monocyte cluster was revealed. IPA was used to generate a signaling pathway associated with allergic asthma induced by Alox15 with genes expressed in the monocyte cluster.