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. 2021 Jul 30;17:2489–2498. doi: 10.2147/NDT.S316136

Figure 4.

Figure 4

EPO-JAK2-STAT5 pathway-related gene and protein expression in the ischemic cortex. (A) Immunohistochemistry was performed to measure the relative protein levels of HIF-1α, EPO, p-JAK2 and p-STAT5 at 72 h post-FCI (400×). (B) MOD of the HIF-1α protein level in each group. (C) MOD of the EPO protein level in each group. (D) MOD of the p-JAK2 protein level in each group. (E) MOD of the p-STAT5 protein level in each group. The data are presented as the mean ± SD (n = 12). Compared to the sham group, *P<0.05. Compared to the model group, #P<0.05. Compared to the AG490-NC group, &P<0.05. Compared to the EA group, P<0.05. Compared to the AG490 group, @P<0.05.