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. 2021 Jul 27;2021:1830790. doi: 10.1155/2021/1830790

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Copyright © 2021 Chen Zou et al.

This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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Loss of LINC01355 inhibited OSCC cell proliferation and induced cell apoptosis. (a) The expression of LINC01355 mRNA was detected by RT-qPCR analysis in HOMEC, CAL27, SCC-15, TSCCA, Tca8113, SCC-9 cells. (b, c) mRNA expression of LINC01355 was detected in CAL27 cells and TSCCA cells when transfected with several shRNAs of LINC01355. (d, e) The cell viability of CAL27 cells and TSCCA cells was analyzed after transfection with shRNA for LINC01355 for 1, 2, 3, and 4 days by CCK8 assay, respectively. (f, g) The cell proliferation of CAL27 cells and TSCCA cells was analyzed after transfection with the specific shRNA for LINC01355 by using EdU assay. (h) The cell colony formation capacity of CAL27 cells and TSCCA cells was analyzed using colony formation assay. (i) The cell apoptosis of CAL27 cells and TSCCA cells was analyzed using flow cytometry assay. ^∗p < 0.05.