Table 2.
Baseline characteristics of subjects with normal hepatic function, and those with mild or moderate hepatic impairment
| Normal [n = 16] | Mild [n = 9] | Moderate [n = 9] | Total [N = 34] | |
|---|---|---|---|---|
| Sex [n (%)] | ||||
| Male | 7 (43.8) | 5 (55.6) | 3 (33.3) | 15 (44.1) |
| Female | 9 (56.3) | 4 (44.4) | 6 (66.7) | 19 (55.9) |
| Age, years | ||||
| Mean (SD) | 54.3 (9.6) | 57.6 (8.0) | 59.8 (9.7) | 56.6 (9.2) |
| Range (min–max) | 37–65 | 44–69 | 37–68 | 37–69 |
| Height, m | ||||
| Mean (SD) | 1.71 (0.1) | 1.68 (0.1) | 1.63 (0.1) | 1.68 (0.1) |
| Range (min–max) | 1.50–1.83 | 1.52–1.83 | 1.55–1.79 | 1.50–1.83 |
| Weight, kg | ||||
| Mean (SD) | 84.9 (17.7) | 75.8 (14.8) | 77.6 (15.5) | 80.6 (16.5) |
| Range (min–max) | 58.0–118.0 | 55.4–94.0 | 50.0–100.0 | 50.0–118.0 |
| BMI, kg/m2 | ||||
| Mean (SD) | 29.0 (5.0) | 26.7 (4.4) | 29.3 (5.5) | 28.5 (5.0) |
| Range (min–max) | 21.7–35.6 | 23.3–32.7 | 20.5–35.7 | 20.5–35.7 |
BMI body mass index, min minimum, max maximum, n number of subjects, SD standard deviation