Table 3. Anthropometric, physiological, and functional variables at T₁ and p-values of the differences between T₁ and T₀ within the groups^a and between the groups.^b,c .

Variable	<75% group	pa	≥75% group	pa	pb
BMI, kg/m2	28.0 (24.0-30.0)	0.87	27.8 (25.2-35.0)	0.68	0.32
PaO2, mmHg	84.3 ± 8.1	0.22	83.4 ± 6.4	0.29	0.76
PaCO2, mmHg	36.8 ± 2.9	0.46	37.6 ± 2.9	0.17	0.49
pH	7.421 ± 0.03	0.005	7.417 ± 0.03	0.85	0.69
SaO2, %	96.8 ± 1.1	0.29	96.8 ± 0.8	0.55	0.95
PaO2/FiO2	401.7 ± 38.8	0.22	397.2 ± 30.6	0.29	0.76
MIP, cmH2O	84.5 ± 25.6	0.91	93.5 ± 21.8	0.01	0.31
MIP, % predicted	103.7 ± 28.1	0.87	121.6 ± 40.3	0.02	0.17
MEP, cmH2O	133.3 ± 46.5	0.03	144.7 ± 47.3	0.29	0.51
MEP, % predicted	119.9 ± 28.9	0.03	134.3 ± 35.7	0.35	0.24
FEV1, L	2.8 ± 0.8	0.66	3.0 ± 1.0	0.01	0.63
FEV1, % predicted	101.3 ± 21.9	0.72	103.5 ± 18.4	0.04	0.77
FVC, L	3.3 (2.7-4.7)	0.12	3.6 (2.7-5.0)	0.02	1.00
FVC, % predicted	106 (77-123)	0.48	96 (88.127)	0.02	1.00
FEV1/FVC	75.0 ± 9.1	0.13	78.1 ± 6.7	0.56	0.30
BI-d score	2 (0-5)	0.0007	0 (0-2)	0.20	0.09
∆BI-d score	−10.9 ± 9.5	-	−1.0 ± 4.6	-	0.002
SPPB total score	10 (10-12)	0.003	12 (12-12)	0.06	0.007
∆SPPB total score	+2.3 ± 2.4	-	+0.7 ± 1.3	-	0.03
SPPB, % predicted	94.4 (90.8-102.2)	0.002	101.9 (100.1-102.6)	0.06	0.02
6MWD, m	479.4 ± 65.9	0.0001	545.2 ± 95.2	0.004	0.04
∆6MWD, m	+158 (100-200)	-	+43 (5-97)	-	0.0001
6MWD, % predicted	94.1 ± 12.2	0.0005	109.5 ± 10.8	0.003	0.001
∆6MWD, % predicted	+28.0 (19.0-44.0)	-	+9.0 (3.0-19.0)	-	0.0005
SpO2mean, %	93.8 (90.0-95.1)	0.94	95.2 (94.5-96.1)	0.90	0.05
SpO2nadir, %	92 (88-93)	0.23	94 (93-96)	0.52	0.04
∆SpO2 baseline/nadir, %	−4 (−8.3 to −2.6)	0.15	−3 (−4.3 to −0.5)	0.97	0.15
EuroQoL-VAS score	78.7 ± 14.2	0.91	85.7 ± 11.5	0.06	0.15

BI-d: Barthel index dyspnea; SPPB: Short Physical Performance Battery; 6MWD: six-minute walk distance; and EuroQoL-VAS: Euro Quality of Life Visual Analogue Scale. ^aValues expressed as mean ± SD or median (IQR).