Table 4. Safety profile of adjuvant chemotherapy with cisplatin and vinorelbine in patients with non-small cell lung cancer after surgery.
Profile | Present study | ANITA triala |
---|---|---|
Grade 3-4 toxicity | 89% | N/A |
Grade 5 toxicity | 9% | 2% |
Grade 3-4 febrile neutropenia | 29% | 9% |
Toxicity as reason for chemotherapy discontinuation | 68% | 34% |
Hospitalization due to toxicity | 49% | N/A |
Results based on Douillard et al. 4 ) ANITA: Adjuvant Navelbine International Trialist Association.