Figure 5.

Comparison of tumor infiltrating immune cells between low and high apoptosis score tumors. Boxplots of comparison of Apoptosis score with (A) Anti-cancer immune cells: CD8, CD4 memory, T helper type 1 (Th1) cells, M1 macrophages and Dendritic cell (DC); and (B) Pro-cancer immune cells: regulatory T cell (Treg), T helper type 2 (Th2) cells, M2 macrophage, B cell and Plasma cells by low and high apoptosis score in the TCGA and METABRIC cohorts. (C) Comparison of low and high apoptosis scores with cytolytic activity in the TCGA and METABRIC cohorts. The median was used as cut-off to divide into high and low score groups within each cohort. Mann-Whitney U test was used to calculate P values. Turkey type box plots show median and inter-quartile level values.