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. 2021 Jul 21;27:1609784. doi: 10.3389/pore.2021.1609784

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Copyright © 2021 Xu, Yuan, Wang, Chen, Zhang and Zhang.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Methylation differences of the two CpG signatures between normal and CRC samples of TCGA-COAD (A), GSE79740 (B), and GSE42752 (C) datasets. p-values are calculated by Wilcoxon rank sum test.