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. 2021 Jul 10;24(8):102847. doi: 10.1016/j.isci.2021.102847

Figure 6.

Figure 6

BMDM–HG-exo modulate macrophage energy metabolism

(A and B) (A) Graph showing representative seahorse extracellular flux analysis of oxygen consumption rate (OCR) and (B) extracellular acidification rate (ECAR) in BMDM exposed to PBS, BMDM–NG-exo or BMDM–HG-exo for 24 hr. One representative experiment out of two experiments is shown n = 13–14 per group).

(C) Bar graphs showing quantified cell-normalized mitochondrial OCR from stress tests. Results are presented relative to PBS control.

(D) Bar graphs showing quantified cell-normalized glycolytic pathway. Results from a pool of two independent experiments is shown, n = 12–14 in each group. ∗p< 0.05, ∗∗p< 0.01, ∗∗∗p< 0.001 as determined by one-way ANOVA and Holm-Sidak post test. Data are represented as mean ± SEM.