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. 2021 Jul 9;53(7):1148–1158. doi: 10.1038/s12276-021-00646-3

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© The Author(s) 2021

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Fig. 4 — a Representative image of whole-cell patch-clamp of a neuron in the dorsal striatum. b Timeline of whole-cell patch-clamp. c Representative traces of tonic GABA recording (left) and sIPSC currents. d Quantification of tonic GABA currents (N = 5 mice for each group). Tonic GABA current is significantly reduced by MAO-B inhibition (KDS2010), but not by MAO-A inhibition (clorgiline). e Quantification of sIPSC amplitudes. f Quantification of sIPSC frequency. Data represent mean ± SEM. **P < 0.01; ns, non-significant by Kruskal-Wallis test with Dunn’s multiple comparison test (d, e) or Brown-Forsythe and Welch ANOVA test with Dunnett’s multiple comparison test (f).