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. 2021 Aug 3;11:15701. doi: 10.1038/s41598-021-95209-x

Figure 4.

Figure 4

Sequential determination of plasma markers cfDNA and Gas6 in COVID-19 patients on ICU and 30-day mortality. Plasma from COVID-19 ICU patients was tested for the presence of cfDNA (A,B), and Gas6 (C,D) during early days (day 1–5), and during late days (> day 6). Survival is based on 30-day mortality. The average plasma marker levels were calculated per group for 33 patients (24 survivors and 8 non-survivors). P-values were calculated between survivors and non-survivors in both early and late days with the Mann–Whitney U test. P-value were considered significant if p < 0.05; * 0.05, ** 0.01, *** 0.001. P-values were calculated between early and late groups divided by survival with the Wilcoxon matched-pairs signed rank test. P-value were considered significant if p < 0.05; # 0.05, ## 0.01, ### 0.001.