Table 1.
Demographic and baseline characteristics of 111 patients on admission to the Intensive Care Unit.
| ICU Covid-19 n = 100 |
ICU Control n = 11 |
P | |
|---|---|---|---|
| Age, yrs, median | 62 (51–73) | 70 (59–75) | 0.225 |
| Gender, male N | 74 (74) | 5 (45.5) | 0.075 |
| BMI | 29 (26–33) | 27.7 (25.4–31.8) | 0.675 |
| Respiratory rate, breaths/min | 28 (23–36) | 15 (15–17) | < 0.001 |
| Heart rate, beats/min | 89 (77–100) | 80 (72–92) | 0.179 |
| MAP, mmHg | 89 (79–97) | 80 (67–86) | 0.012 |
| Temperature, °C | 38.0 (37.5–38.7) | 36.4 (36.4–36.7) | < 0.001 |
| Diabetes, yes | 29 (29) | 2 (18.2) | 0.725 |
| Hypertension, yes | 52 (52) | 4 (36.4) | 0.325 |
| Heart failure, yes | 5 (5) | 1 (9.1) | 0.474 |
| Ischemic heart failure, yes | 12 (12) | 0 (0) | 0.605 |
| Vessel disease, yes | 17 (17) | 1 (9.1) | 0.689 |
| Malign disease, yes | 6 (6) | 11 (100) | < 0.001 |
| HIPEC surgery, yes | 0 (0) | 11 (100) | < 0.001 |
| PaO2/FiO2-ratio, mmHg | 138.1 (116.3–178.1) | 271.5 (227.3–373.9) | 0.001 |
| Ventilation, yes | 100 (100) | 11 (100) | 1.000 |
| Mechanical ventilation | 12 (12) | 6 (54.5) | < 0.001 |
| Non-invasive ventilation | 88 (88) | 5 (45.5) | |
| Pulmonary disease, yes | 23 (23) | 1 (9.1) | 0.451 |
| Asthma | 15 (15) | 1 (9.1) | |
| COPD | 6 (6) | ||
| Sarcoidosis | 1 (1) | ||
| Smoker | |||
| No | 75 (75) | 9 (81.8) | 0.797 |
| Yes | 4 (4) | 0 (0) | |
| Previous | 18 (18) | 2 (18.2) | |
| Unknown | 3 (3) | ||
| Renal replacement therapy, yes | 0 (0) | 0 (0) | 1.000 |
| AKI, yes | 63 (63) | 0 (0) | < 0.001 |
| Steroid treatment, yes | 10 (10) | 1 (9.1) | 0.916 |
| ACEi/ARB treatment, yes | 37 (37) | 2 (18.2) | 0.332 |
| Anticoagulant treatment, yes | 22 (22) | 5 (45.5) | 0.132 |
| Vasoactive treatment, yes | 5 (5) | 6 (54.5) | < 0.001 |
| Antibiotic treatment, yes | 60 (60) | 8 (72.7) | 0.527 |
| SAPS-3 | 53 (47–58) | 54 (49–58) | 0.462 |
| SOFA | 6 (4–7) | 6 (6–8) | 0.885 |
Values are represented as median (IQR) or n (%). The p-value is calculated for continuous parameters with the Mann–Whitney U test, and for categorical parameters the chi-square test; p < 0.05 is considered significant.
BMI body mass index, MAP mean arterial pressure, HIPEC heated intraperitoneal chemotherapy, COPD chronic obstructive pulmonary disease, ACEi/ARB angiotensin-converting enzyme inhibitor/angiotensin receptor blockers, SAPS simplified acute physiology score, SOFA sequential organ failure assessment.