Table 3.
Sensitivity and subgroup analysis for CDR and recall rate.
| Subgroup | CDR/1000 (95 % CI) |
Recall rate/100 (95 % CI) |
||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| N | RD | p | I2 | pinteraction | N | RD | p | I2 | pinteraction | |
| SM/DBT vs DM/DBT | ||||||||||
| US/annual/retrospective | 5 | 0.0 (−0.6 to 0.5) | 0.947 | 0 | 0.722 | 5 | −0.87 (−1.40 to −0.35) | 0.001 | 82 % | <0.001 |
| Other/biennial/prospective | 2 | −0.1 (−0.6 to 0.4) | 0.741 | 32 % | 2 | 0.09 (−0.67 to 0.85) | 0.817 | 90 % | ||
| Double reading | 1 | 0.3 (−0.5 to 1.1) | 0.466 | – | 0.299 | 1 | 0.51 (0.06–0.95) | 0.025 | – | <0.001 |
| Single reading | 6 | −0.2 (−0.5 to 0.2) | 0.345 | 0 | 6 | −0.75 (−1.20 to −0.29) | 0.001 | 88 % | ||
| SM/DBT vs DM | ||||||||||
| US/annual/retrospective | 3 | 1.1 (0.1–2.1) | 0.037 | 40 % | 0.058 | 3 | −3.39 (−4.53 to −2.26) | <0.01 | 95 % | <0.001 |
| Other/biennial/prospective | 8 | 2.3 (1.6–3.0) | <0.001 | 65 % | 7 | 0.05 (−0.43 to 0.53) | 0.839 | 93 % | ||
| Double reading | 6 | 2.8 (2.0–3.6) | <0.001 | 40 % | <0.001 | 6 | −0.09 (−0.51 to 0.68) | 0.773 | 94 % | <0.001 |
| Single reading | 5 | 1.4 (1.0–1.9) | <0.001 | 12 % | 4 | −2.56 (−4.60 to −0.52) | 0.014 | 99 % | ||
CDR cancer detection rate, SM synthesized mammography, DBT digital breast tomosynthesis, DM digital mammography, CI confidence interval, RD risk difference, N number of study.