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. 2021 Aug 3;11:15754. doi: 10.1038/s41598-021-94456-2

Table 6.

ROC analysis to screening the severity of fibromyalgia symptoms according to the right and left PFC activation based on Δ-HbO* (n = 22).

AUC 95% CI CI 95% Cutoffs Sensitivity 1 − Specificity
Portuguese Profile of Chronic Pain Screen (BP-PCP:S) total score
Δ-HbO* based on the HbO level before thermal stimuli onset and 15 s after on the left PFC (mM)
 0.58 (CI 95%, 0.21–0.95) − 0.175 100 100
Δ-HbO* based on the HbO level before thermal stimuli onset and 15 s after on the right PFC (mM)
 0.59 (CI 95%, 0.20–0.97) − 0.20 100 100
Central Sensitization Inventory (BP-SCI) total score
Δ-HbO* based on the HbO level before thermal stimuli onset and 15 s after on the left PFC (mM)
 0.82 (CI 95%, 0.61–100) − 0.175 100 100
Δ-HbO based on the HbO level before thermal stimuli onset and 15 s after on the right PFC (mM)
 0.68 (CI 95%, 0.29–100) − 0.20 100 100

AUC area under the curve, CI confidence interval, ROC receiver operator characteristics, mM millimolar.