Table 4.
Multivariable regression analysis for the endpoint Textbook Outcome.
| Factors | OR (95% CI) | p-value |
|---|---|---|
| Patients analyzed: n = 53 | ||
| Target factor: Textbook Outcome | ||
| Age | 1.00 (0.99; 1.02) | 0.508 |
| Comorbidity | 1.76 (0.11; 31.24) | 0.682 |
| Underweight | 14.56 (0.87; 7.40*102) | 0.108 |
| ASA Score (33) | 0.30 (0.02; 2.17) | 0.275 |
| Previous abdominal surgery | 1.29 (0.07; 47.93) | 0.875 |
| Primary liver tumor (34) | 4.22 (0.45; 64.61) | 0.241 |
| Malignancy (34) | 0.93 (0.05; 25.83) | 0.959 |
| Neoadjuvant chemotherapy (35) | 5.09 (0.02; 2.02*103) | 0.557 |
| Preoperative Hemoglobin level (36) | 1.38 (0.87; 2.57) | 0.219 |
| Operation time | 1.00 (0.99; 1.02) | 0.614 |
| Intraoperative blood loss* (3, 10, 36) | 0.85 (0.69; 0.97) | 0.048 |
| Severe intraoperative hemorrhage† (3, 36) | 7.15*10-5 (NA; 7.93*1082) | 0.554 |
| Intraoperative blood transfusion (37, 38) | 0.95 (0.79; 1.11) | 0.997 |
| Anatomical resection performed (15) | 0.73 (0.01; 39.61) | 0.872 |
| Number of segments resected | 0.55 (0.13; 1.79) | 0.342 |
| Vascular or non-hepatic visceral resection performed (3) | 0.32 (0.01; 21.09) | 0.602 |
To adjust intraoperative blood loss and transfusion for age and bodyweight, the total amount in milliliters was divided by the estimated circulating blood volume (CBV) in milliliters. CBV was calculated using a method validated by Schmidt and Thews (39).
Severe hemorrhage was defined as intraoperative blood loss > than 50% of CBV (3).