Table 5.
Multivariable regression analysis for the endpoint Comprehensive Complication Index.
| Factors | Estimate b (95% CI) | p-value |
|---|---|---|
| Patients analyzed: n = 53 | ||
| Target factor: Comprehensive Complication Index | ||
| Age | 0.01 (−0.06; 0.09) | 0.751 |
| Comorbidity | 7.44 (−7.60; 22.48) | 0.322 |
| Underweight | −6.86 (−17.52; 3.80) | 0.200 |
| ASA Score (33) | 1.30 (−6.56; 9.15) | 0.740 |
| Previous abdominal surgery | 0.89 (−13.56; 15.34) | 0.901 |
| Primary liver tumor (34) | −1.73 (−13.23; 9.78) | 0.762 |
| Malignancy (34) | −0.11 (−17.82; 17.60) | 0.990 |
| Neoadjuvant chemotherapy (35) | −6.38 (−32.76; 20.00) | 0.627 |
| Preoperative Hemoglobin level (36) | −3.42 (−5.91; −0.93) | 0.008 |
| Operation time | 0.03 (-0.05; 0.11) | 0.454 |
| Intraoperative blood loss* (3, 10, 36) | 0.77 (0.22; 1.32) | 0.008 |
| Severe intraoperative hemorrhage† (3, 36) | −14.10 (−43.47; 15.27) | 0.337 |
| Intraoperative blood transfusion (37, 38) | −0.41 (−1.01; 0.20) | 0.180 |
| Anatomical resection performed (15) | 6.09 (−13.28; 25.47) | 0.528 |
| Number of segments resected | −0.61 (−6.20; 4.99) | 0.827 |
| Vascular or non-hepatic visceral resection performed (3) | 0.04 (−20.94; 21.02) | 0.997 |
*
To adjust intraoperative blood loss and transfusion for age and bodyweight, the total amount in milliliters was divided by the estimated circulating blood volume (CBV) in milliliters. CBV was calculated using a method validated by Schmidt and Thews (39).
†
Severe hemorrhage was defined as intraoperative blood loss > than 50% of CBV (3).