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Effect of vincristine in the structure of the heart (A–C), mesenteric vessels (D–F), and aorta (G–I). Masson’s trichrome stain of saline (A, D, G), animals treated with vincristine (B, E, H) or vincristine-treated animals 2 weeks after treatment (C, F). Bar: 100 μm. Mean thickness of the aortic tunica media (I), obtained from 4–6 different animals. Data represent the mean ± SEM. Saline vs. vincristine (***p < 0.001).
