FIGURE 5.
(A) Concentration-response curve of phenylephrine (10–80 nmol), (B) concentration-response curve of carbachol (3·10−10 mol–3·10−5 mol), and (C) concentration-response curve of sodium nitroprusside (SNP) (3·10−11 mol–3·10−6 mol) in perfused mesenteric bed from animals chronically treated with saline (saline treatment, white squares) or vincristine (vincristine treatment, black squares). Values are expressed as mean ± SEM, n = 9–13 preparations per experimental group. A two-way ANOVA followed by the Bonferroni test was used for statistical analysis (***p < 0.001, **p < 0.01, vincristine treatment vs. saline treatment).