Fig. 1.

NVP‐BEZ235 and AZD5363 modulate signaling pathways in a dose‐dependent manner. (A) Cell lines were treated with increasing concentration of NVP‐BEZ235 (0–5 μm). Western blot was performed using relevant antibodies, and β‐actin was used as a loading control. Results shown are representative of three independent experiments. (B) Cell lines were treated with increasing concentration of AZD5363 (0–20 μm). Western blot was performed using relevant antibodies, and β‐actin was used as a loading control. Results shown are representative of three independent experiments. [Colour figure can be viewed at wileyonlinelibrary.com]