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. 2021 Aug 4;43(4):788–796. doi: 10.1038/s41401-021-00735-z

Fig. 1. Comparison of RBD binding affinities with Apo ACE2 and ACE2 treated with MLN-4760 by BLI.

Fig. 1

Association and dissociation curves of RBD with Apo ACE2 (a) or ACE2 treated with MLN-4760 (b) in a concentration range between 4.68 nM and 150 nM. The number that follows the ±sign is the standard deviation (SD). (c) Comparison of binding conformations between the binding complex of RBD with Apo ACE2 (PDB code: 1R42) and Holo ACE2 (PDB code: 1R4L). The conformational alignment was performed on the first 100 residues at the N-terminus of ACE2.