Table 1.

Relationship Between Glypican-1 expression and Demographic and Clinicopathological Features

Characteristic	Negative	Low	Moderate	Strong	P value
Age (years)
≤ 50 (n=135, 59.3%)	4 (3%)	19 (14.1%)	28 (20.7%)	84 (62.2%)	0.178
> 50 (n=93, 40.7%)	0 (0%)	10 (10.8%)	16 (17.2%)	67 (72%)
Histological type
Normal (n=5, 2.2%)	4 (80%)	1 (20%)	0 (0%)	0 (0%)	0.011
Benign (n=3, 1.3%)	0 (0%)	3 (100%)	0 (0%)	0 (0%)
Invasive ductal carcinoma (n=179, 78.5%)	0 (0%)	19 (10.6%)	36 (20.1%)	124 (69.3%)
Invasive lobular carcinoma (n=12, 5.3%)	0 (0%)	2 (16.7%)	1 (8.3%)	9 (75%)
Intra-ductal carcinoma (n=14, 6.1%)	0 (0%)	3 (21.4%)	3 (14.3%)	9 (64.3%)
Mucinous adenocarcinoma (n=6, 2.6%)	0 (0%)	0 (0%)	2 (33.3%)	4 (66.7%)
Invasive papillary carcinoma (n=2, 0.9%)	0 (0%)	0 (0%)	0 (0%)	2 (100%)
Lobular carcinoma in situ (n=2, 0.9%)	0 (0%)	0 (0%)	2 (100%)	0 (0%)
Invasive apocrine carcinoma (n=1, 0.4%)	0 (0%)	1 (100%)	0 (0%)	0 (0%)
Paget’s disease (n=1, 0.4%)	0 (0%)	0 (0%)	1 (100%)	0 (0%)
Lipid-rich carcinoma (n=1, 0.4%)	0 (0%)	0 (0%)	0 (0%)	1 (100%)
Adenoid cystic carcinoma (n=1, 0.4%)	0 (0%)	0 (0%)	0 (0%)	1 (100%)
Undifferentiated carcinoma (n=1, 0.4%)	0 (0%)	0 (0%)	0 (0%)	1 (100%)
Histological grade
I (n=19, 8.6%)	0 (0%)	4 (16%)	5 (11.4%)	10 (6.6%)	0.037
II (n=87, 39.5%)	0 (0%)	9 (36%)	12 (27.3%)	66 (43.7%)
III (n=114, 51.8%)	0 (0%)	12 (48%)	27 (61.4%)	75 (49.7%)
Lymph node metastasis
Yes (n=61, 27.7%)	0 (0%)	3 (4.9%)	13 (21.3%)	45 (73.8%)	0.169
No (n=159, 72.3%)	0 (0%)	22 (13.8%)	31 (19.5%)	106 (66.7%)
Tumour size
Tis (n=17, 7.7%)	0 (0%)	5 (29.4%)	4 (23.5%)	8 (47.1%)	0.003
T1 (n=22, 10%)	0 (0%)	3 (13.6%)	8 (36.4%)	11 (50%)
T2 (n=135, 61.4%)	0 (0%)	17 (12.6%)	22 (16.3%)	96 (71.1%)
T3 (n=30, 13.6%)	0 (0%)	0 (0%)	5 (16.7%)	25 (83.3%)
T4 (n=16, 7.3%)	0 (0%)	0 (0%)	5 (31.3%)	11 (68.8%)