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. 2021 Jul 21;12:644451. doi: 10.3389/fgene.2021.644451

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Copyright © 2021 Liang, Meng and Qiu.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Circ_0013958 was upregulated, while miR-637 was downregulated in OC tissues and cells. (A) QRT-PCR assay for the expression of circ_0013958 in OC tissues and adjacent normal tissues (n = 30). (B) QRT-PCR analysis for the expression of circ_0013958 in OC cell line (SKOV3 and CAOV3) and human ovarian surface epithelial cells (HOSE). (C) ROC curve analysis of the prognostic sensitivity and specificity of circ_0013958 in OC patients in accordance with the 5-year survival of OC patients. (D) QRT-PCR assay for the expression of miR-637 in OC tissues and matched normal tissues (n = 30). (E) QRT-PCR assay for the expression of miR-637 in HOSE, SKOV3, and CAOV3 cells. (F) Pearson's correlation analysis for the correlation between the expression levels of circ_0013958 and miR-637 in OC tissues (n = 30). *P < 0.05; **P < 0.01.