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. 2021 Jul 22;59:256–269. doi: 10.1016/j.breast.2021.07.015

Table 1.

Features of included studies: design, patients, and tumor characteristics.

Author (year) Center Design Origin T/N stage before NACT
Method of pre-NAC node status assessment
T stage N stage
[25] Single Prospective USA T1–T4 N1–N3 FNA
[26] Single Retrospective Turkey T0–T4 N1–N2 NR
[27] Multiple Prospective Canada T0–T3 N1–N2 FNA or CNB
[16] Multiple Prospective USA T0–T4 N1–N2 FNA or CNB
[28] Single Retrospective USA T1–T3 N1–N3 FNA
[29] Single Prospective Italy T2–T4 N1–N3 Palpation & Ultrasound
[30] Single Retrospective India T1–T4 N1–N2 MRI & Ultrasound
[31] Single Prospective Korea T1–T4 N1–N3 FNA
[5] Single Prospective France T1–T4 N1–N2 FNA
[32] Multiple Prospective Japan T1–T3 N1 FNA
[33] Single Retrospective China T1–T4 N1–N3 FNA
[34] Single Prospective Korea T1–T4 N+ NR
[9] Single Retrospective Korea T0–T3 N+ FNA
[10] Multiple Prospective Germany T1–T4 N1–N2 Palpation & Ultrasound
[36] Single Prospective Korea T1–T4 N+ FNA
[35] Single Prospective Korea NR N1–N3 PET/CT & Ultrasound
[11] Single Retrospective USA T1–T4 N+ FNA
[37] Single Retrospective Turkey T1–T4 N1–N2 FNA
[39] Single Retrospective Korea T1–T3 N+ FNA
[38] Single Retrospective Korea T1–T4 N1–N3 FNA
[40] Single Prospective USA T1–T4 N1–N3 FNA
[41] Single Retrospective Japan T1–T4 N1–N3 FNA
[42] Single Prospective India T2–T4 N+ FNA
[43] Single Prospective China T1–T3 N1 FNA
[44] Single Prospective Japan T0–T4 N+ FNA
[45] Single Prospective China NR N+ FNA
[47] Multiple Prospective Sweden T1–T4 N+ FNA

Abbreviations: NACT, neoadjuvant chemotherapy; NR, not reported; FNA, fine needle aspiration; CNB, core needle biopsy; MRI, magnetic resonance imaging; PET/CT, positron emission tomography/computed tomography.