Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2021 May 12;105(2):543–553. doi: 10.1093/biolre/ioab096

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© The Author(s) 2021. Published by Oxford University Press on behalf of Society for the Study of Reproduction.

This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/4.0/), which permits non-commercial re-use, distribution, and reproduction in any medium, provided the original work is properly cited. For commercial re-use, please contact journals.permissions@oup.com

PMC Copyright notice

Acetyl-H3 levels of nuclei of one-cell SCNT-derived embryos treated with chlamydocin analogue HDAC inhibitors. (A) Scheme of the experiment. (B) Representative images of acetyl-H3 immunofluorescence and DNA (DAPI) in the nuclei of one-cell SCNT-derived embryos with or without (control) HDAC inhibitor treatment and IVF-derived embryos. The male and female pronuclei of IVF-derived embryos were analyzed separately. Bar = 5 μm. (C) Relative fluorescent intensity of acetyl-H3 measured. The DAPI density was set to 1. Each dot represents one embryo. The fluorescence levels of all HDAC inhibitor treatment groups were significantly higher than that of the control embryos (P < 0.0001, by Tukey test).