Figure 1. Selection of Pediatric Intensive Care Units (ICUs) and Enrollment of Patients in a Stepped-Wedge, Cluster Randomized Trial of a Sedation and Ventilator Liberation Protocol Intervention in Infants and Children.

IQR indicates interquartile range.

^aOne hospital site had 2 pediatric ICUs that were randomized together to avoid contamination of the intervention.

^bDiagnostic codes associated with a short duration of ventilation (<24 hours) were categorized as short and all others were categorized as prolonged.

^cThere were 3 patients excluded from the analysis because they could not be linked to the Paediatric Intensive Care Audit Network data set.