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. 2021 Jul 21;13:688587. doi: 10.3389/fnagi.2021.688587

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Copyright © 2021 Lin, Shen, Lu, Liang, Zhang, Xie and Dong.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Effects of WS635 on the anesthesia/surgery-induced changes in the amounts of postsynaptic density (PSD)-95 and synaptophysin in the hippocampus and cortex of mice. Effects of WS365 (52.8 mg/kg) and vehicle (DMSO) on the anesthesia/surgery-induced changes in the amounts of PSD-95 in the hippocampus (A,B) and cortex (C,D) of the mice on day 13 after the anesthesia/surgery. Effects of WS365 (52.8 mg/kg) and vehicle (DMSO) on the anesthesia/surgery-induced changes in the amounts of synaptophysin in the hippocampus (E,F) and cortex (G,H) of the mice on day 13 after the anesthesia/surgery. N = 6 mice in each group, * or ^#P < 0.05; ** or ^##P < 0.01; *** P < 0.001. Two-way ANOVA with the post hoc test (Bonferroni correction) was used. P values refer to the difference among different conditions on the amounts of the PSD-95 and synaptophysin. DMSO, dimethyl sulfoxide.