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. 2021 Jul 21;12:713647. doi: 10.3389/fimmu.2021.713647

Figure 6.

Figure 6

Toothbrushing reduces the number of metabolites in PBC saliva more than that in HC saliva. (A) OPLS-DA plot of the salivary metabolome profile in PBC and HC saliva before and after toothbrushing. (B) Metabolites that were significantly altered in both PBC and HC saliva from before to after toothbrushing. (C) Metabolites that were significantly altered only in PBC saliva from before to after toothbrushing. *P < 0.05; **P < 0.01 and ***P < 0.001.