Figure 4.

Temperament genome-wide association study (GWAS) reveals an intron variant (CFA15:23,340,008 A>T) of ACSS3 gene. Manhattan plots showing the association of whole genome variants with temperament levels in dogs. Bonferroni and suggestive thresholds are indicated with red and blue lines. (A) Without including body size as a covariate. The ACSS3 intron variant is above the suggestive threshold. (B) Including body size as a covariate. The ACSS3 intron variant is above the Bonferroni threshold.