TABLE 1.
Relationship between circTASP1 expression and clinical characteristics of patients with acute myeloid leukaemia
| Characteristics | Number of patients | circTASP1 High expression | circTASP1 Low expression | P value |
|---|---|---|---|---|
| Age (mean) | 49.3 ± 19 | 51.08 ± 20 | .752 | |
| Sex | ||||
| Male | 36 | 17 | 19 | .598 |
| Female | 24 | 13 | 11 | |
| WBC/ × 109/L | ||||
| ≥10 | 47 | 23 | 24 | .754 |
| <10 | 13 | 7 | 6 | |
| PLT × 109/L | ||||
| ≥50 | 25 | 13 | 12 | .793 |
| <50 | 35 | 17 | 18 | |
| HGB (g/L) | ||||
| ≥90 | 35 | 22 | 13 | .018 * |
| <90 | 25 | 8 | 17 | |
| CEBPα | ||||
| Positive | 26 | 9 | 17 | .037 * |
| Negative | 34 | 21 | 13 | |
| NPM1 | ||||
| Mutation | 19 | 9 | 10 | .781 |
| Wild type | 41 | 21 | 20 | |
| FLT3‐ITD | ||||
| Positive | 24 | 14 | 10 | .292 |
| Negative | 36 | 16 | 20 | |
| IDH1/2 | ||||
| Positive | 18 | 11 | 7 | .260 |
| Negative | 42 | 19 | 23 | |
| DNMT3A | ||||
| Positive | 30 | 16 | 14 | .606 |
| Negative | 30 | 14 | 16 | |
| FAB subtypes | ||||
| M1 | 9 | 5 | 4 | .661 |
| M2 | 31 | 13 | 18 | |
| M3 | 4 | 2 | 2 | |
| M4 | 12 | 7 | 5 | |
| M5 | 2 | 2 | 0 | |
| M6 | 2 | 1 | 1 | |
| Marrow blast | ||||
| ≥0.6000 | 34 | 15 | 19 | .297 |
| <0.6000 | 26 | 15 | 11 | |
| Karyotype | ||||
| Normal | 43 | 21 | 22 | .554 |
| Complex | 10 | 4 | 6 | |
| inv(16)/CBFβ‐MYH11 | 1 | 1 | 0 | |
| Others | 6 | 4 | 2 | |
*
P < .05.