FIGURE 1.

A, MTT cytotoxicity assay for cell viability evaluation. B, Effect of TS exposure and TBI on level of thrombomodulin. Levels of thrombomodulin in the supernatants collected at 24 h after TBI was measured by ELISA. TS exposure promoted suppression of thrombomodulin and potentially impaired blood haemostasis. n = 6 biological replicates, *P < .05, **P < .01, ***P < .001, ****P < .0001 vs control. ⁺ P < .05, ⁺⁺ P < .01, ⁺⁺⁺ P < .001, ⁺⁺⁺⁺ P < .0001 vs smoked group. ^@ P < .05, ^@@ P < .01, ^@@@ P < .001, ^@@@@ P < .0001 vs TBI‐induced group