FIGURE 1.

Up‐regulated expression of miR‐130b‐5p during HSC activation. A, The protein expression level of α‐SMA was increased in activated HSC‐T6 cells induced by 10 ng/mL TGF‐β1 at different time points. B, The mRNA expression of α‐SMA was increased in activated HSC‐T6 cells induced by 10 ng/mL TGF‐β1 at different time points. C, α‐SMA (red) was identified by immunofluorescence assays in HSC‐T6 cells induced by 10 ng/mL TGF‐β1 at different time points. D, MicroRNA microarray analysis results in quiescent and activated HSCs. E, The expression level of miR‐130b‐5p was detected by quantitative real‐time PCR. F, The expression level of miR‐130b‐5p in activated HSCs was detected at different time points. Data represent means ± SEM of at least three independent experiments. *P < .05, **P < .01 and ***<.001