Skip to main content
. 2021 Jul 2;25(15):7342–7353. doi: 10.1111/jcmm.16763

FIGURE 1.

FIGURE 1

Abnormal Glu, 5‐HT, DA levels and depressive‐like behaviour in DD rats. (A) Experimental protocol. Rats were adaptively fed for 3 days then given to a high‐fat diet for 2 weeks and injected with STZ and followed by subjected CUMS for 21 days to establish the DD model. (B) Blood‐glucose levels detected by a blood‐glucose sensor in control and DD model group (n = 5; **P < .001 vs Con). (C) Glutamate content detected by ELISA in control and DD model group (n = 4; **P < .001 vs Con). (D‐E) 5‐HT and DA levels detected by ELISA in control and DD model group (n = 4; *P < .05, **P < .001 vs Con). (F‐G) Number of activities in the open‐field test and the immobility time in the forced swimming test (n = 5; **P < .001 vs Con)