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. 2021 Jul 16;25(15):7545–7558. doi: 10.1111/jcmm.16790

FIGURE 4.

FIGURE 4

NOD2 was the key immune gene in the TME and acted as a tumour suppressor in LUAD. (A) Gene expression correlations of 13 PDEIRGs. Lines between two genes indicate the correlation value calculated by Pearson coefficient of correlation test. (B and C) PPI networks of 13 PDEIRGs from STRING database (B) and ordered by the number of connected nodes (C). (D) NOD2 expressions in different immunity clusters of the entire TCGA LUAD patients (n = 422). (E) NOD2 expressions in the high‐risk group and the low‐risk group of the entire TCGA LUAD patients (n = 422). (F) NOD2 expressions of the entire TCGA LUAD patients with different tumour sizes (T stage, n = 422). (G) NOD2 expressions of the entire TCGA LUAD patients with and without metastasis (M stage, n = 422). (H) NOD2 expressions of the entire TCGA LUAD patients with different TNM stages (n = 422)