. Author manuscript; available in PMC: 2021 Dec 1.

Published in final edited form as: Leuk Lymphoma. 2020 Jul 15;61(12):2939–2946. doi: 10.1080/10428194.2020.1791850

Table 2:

Association of Time to 1st and Time to 2nd Treatment with Overall Survival

	Association	modified Kτ	95% CI	P value
Initial Observation	TT1T and OS	0.055	−0.19 to 0.22	0.603
Initial Observation	TT2T and OS	0.46	0.22 to 0.59	0.004
Immediate Therapy	TT1T and OS	0.20	0.05 to 0.31	0.016
Immediate Therapy	TT2T and OS	0.53	0.40 to 0.61	<0.001

TT1T, time to 1^st therapy; TT2T, time from diagnosis to 2^nd treatment; OS, overall survival; modified Kτ, modified Kendall’s tau. TT2T is strongly correlated with OS among patients who are recommended initial observation or immediate therapy, while TT1T is not.