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. 2021 Jul 20;24(3):666. doi: 10.3892/mmr.2021.12305

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Copyright: © Zhan et al.

This is an open access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non-commercial and no modifications or adaptations are made.

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Figure 4. — Overexpression of miR-93 suppresses LPS-induced inflammatory response. miR-93 mimics were added to the cultured TCMK-1 cells 24 h prior to LPS treatment and incubated for 24 h and then cells were harvested for subsequent experiments. Effects of miR-93 on the protein levels of (A) IL-1β, (B) TNF-α and (C) IL-6 in LPS-treated TCMK-1 cells. Effects of miR-93 on mRNA levels of (D) IL-1β, (E) TNF-α and (F) IL-6 in LPS-treated TCMK-1 cells. Data are presented as the mean ± standard deviation of three independent experiments. *P<0.05, **P<0.01 vs. Control group; ^##P<0.01 vs. LPS group. miR, microRNA; LPS, lipopolysaccharide; IL, interleukin; TNF, tumor necrosis factor; NC, negative control.