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Mechanisms of Fcγ‐CRs T cell‐mediated tumor cell elimination. The Fc portion of monoclonal antibody (mAb) attaches to the Fcγ‐CRs on the surface of Fcγ‐CRs T cells. Following the recognition of GB‐associated antigen and binding of the Fcγ‐CRs T with the mAb, the Fcγ‐CRs T cells are activated leading to the induction of cell‐mediated cytotoxicity either through the release of cytotoxic granules and/or the induction of Fcγ‐CRs dependent FAS expression (lower panel)
