TABLE 1.
Baseline study characteristics for patients with advanced cancer
| Characteristics N = 346 | No. (%) α | ||
|---|---|---|---|
| Genomics informed (n = 140) | Standard care (n = 206) | p‐value τ | |
| Gender, female | 86 (61.43) | 149 (72.33) | 0.033 |
| Age at index, mean (SD) | 54.69 (13.58) | 54.68 (12.24) | 0.997 |
| Geographic area classification | 0.082 | ||
| Urban | 106 (75.71) | 161 (78.16) | |
| Rural | 32 (22.86) | 33 (16.02) | |
| Mixed | 1 (0.71) | 10 (4.85) | |
| LHA missing | 1 (0.71) | 2 (0.97) | |
| Primary cancer site | 0.865 | ||
| Breast | 42 (30.00) | 75 (36.41) | |
| Gastrointestinal | 30 (21.43) | 41 (19.90) | |
| Lung | 14 (10.00) | 20 (9.71) | |
| Sarcoma | 16 (11.43) | 15 (7.28) | |
| Pancreas | 6 (4.29) | 12 (5.83) | |
| Gynecological | 10 (7.14) | 15 (7.28) | |
| Other | 22 (15.71) | 28 (13.59) | |
| Year of diagnosis, mean (SD) | 2009.91 (7.77) | 2010.66 (5.81) | 0.303 |
| Stage at diagnosis | 0.883 | ||
| Stage I | 14 (10.00) | 21 (10.19) | |
| Stage II | 14 (10.00) | 27 (13.11) | |
| Stage III | 10 (7.14) | 16 (7.77) | |
| Stage IV | 23 (16.43) | 31 (15.05) | |
| REC, UNK, or NCR | 79 (56.43) | 111 (53.88) | |
| Number of lines prior to index date, mean (SD) | 2.71 (1.74) | 2.64 (1.66) | 0.720 |
Abbreviations: SD, standard deviation; REC, UNK, or NCR, recurrent, stage unknown, or no classification recommended. Significance level: p < 0.007 (= 0.05/7) after Bonferroni correction.
α
Frequencies and percentages reported for categorical variables, means, and standard deviations reported for continuous variables.
τ
p‐value from Chi‐square tests for categorical variables and paired t‐tests for continuous variables.