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. 2021 Aug 4;9:30. doi: 10.1186/s40170-021-00266-5

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© The Author(s) 2021

Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated in a credit line to the data.

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Fig. 5 — The correlation between CSC markers and proteins involved in lipid metabolism and their importance in the patient’s outcome. A The correlation heatmap with a hierarchical clustering of the levels of CSC markers and proteins involved in lipid metabolism. The magnitude of the correlation is shown by the colors with red representing a positive correlation and blue a negative correlation. B Kaplan-Meier curves representing the correlation between protein expression and recurrence. Low represents a low protein expression, high represents a high protein expression. CD cluster of differentiation, EpCAM epithelial cell adhesion molecule, ACLY ATP citrate lyase, SCD1 stearoyl-CoA desaturase-1. A p value lower than 0.05 was considered as a significant value